Co-director
Google scholar profile
sophie.caillat@inserm.fr

Prof. Sophie Caillat-Zucman is Head of the Saint-Louis Immunology Department, the largest in France with a unique activity in the field of organ and hematopoietic stem cell transplantation, and in CAR-T cell therapies. She obtained her MD in 1988 before being appointed as Assistant-Professor of Immunology (Université Paris V) and Head of the Histocompatibility Laboratory at Hopital Necker in 1992. Since 2011, she is Professor in Immunology at the Université Paris VII, and President of the French Biomedical Agency board of directors since 2015. Her main research interests pertained to HLAs or to NK cell receptors in autoimmune, infectious or malignant diseases. Her current research projects are focused on human Mucosal-associated invariant T (MAIT) cells and their usage in adoptive immune therapy.

PU-PH
jerome.le-goff@aphp.fr

Jérôme Le Goff is Professor of Virology at the University de Paris and in the Virology department in Saint-Louis hospital, Paris, France.
He obtained a PhD in Virology in the lab of Laurent Belec at the University of Paris Descartes where he studied interactions between HSV-2 and HIV. He then joined the laboratory of Francois Clavel (Inserm U941, Viral Evolution and pathogenesis). He did a post-doc in San Francisco in the Viral Diagnosis and Discovery Center led by Charles Chiu to analyze the gut Virome and its role in the enteric graft-versus host disease.
He finally joined our new research team to study how viruses interplay with the microbiome and host immunity to trigger graft-versus-host disease in hematopoietic stem cell transplant patients, and to investigate the pathogenesis of human adenoviruses and identify new drugs against these viruses.

MCU-PH
ResearchGate Profile
david.michonneau@aphp.fr

David Michonneau is Associate Professor at the University de Paris and hematologist in Saint-Louis hospital. He graduated from the Ecole Normale Supérieure de Lyon in Immunology and Virology in 2005. He obtained a PhD in Immunology in the lab of Philippe Bousso at Pasteur Institute where he studied in vivo dynamic of immune response during Graft versus Host disease and Graft versus Leukemia Effect. He performed medical study in Lyon University and joined APHP in 2007 for his residency in hematology. He obtained a MD in 2012 on the role of donor B cells during GvHD after allogeneic HSCT. In 2015, he finally joined the unit of hematology and transplantation at Saint Louis hospital and our team to study immune system during the alloimmune response in GvL and GvHD. He is currently developing multi-omics approaches to improve our understanding of human immune system, based on mass cytometry, metabolomics and transcriptomics.

Researcher (CR INSERM)
Google Scholar Profile
ResearchGate Profile
mathieu.chevalier@inserm.fr

Mathieu graduated from the Ecole Supérieure de Biotechnologie de Strasbourg (ESBS) in 2009. He started to work in the HIV immunology field with Prof. Hendrik Streeck at the Ragon Institute of MGH, MIT and Harvard in Boston (USA), before joining the Pasteur Institute in Paris as a PhD student (Prof. F. Barré-Sinoussi’s lab). He worked there on acute HIV infection with Prof. L. Weiss and obtained his Ph.D. degree in immunology from the Université Paris VII. He then moved to Lausanne (Switzerland) to work for five years on cancer immune regulation topics with Dr. L. Derré at the Lausanne University Hospital. He finally joined our team to build his own research projects on immunoregulatory networks involved in the graft-versus-leukemia effect.

MCU-PH
david.boutboul@aphp.fr

Post-doctoral researcher
ORCID profile
jennifer.bordenave@inserm.fr

Jennifer is a post-doctoral researcher and works about B-cell reconstitution after hematopoietic stem cell transplantation. After her Master’s degree in Human Physiology, Metabolism and Pathophysiology at the Pierre and Marie Curie University, she obtained her PhD in Pathophysiology from Paris-Saclay University in 2019. During her PhD in C. Guignabert’s team (Paris, France), Jennifer studied the role of pulmonary pericytes in Pulmonary arterial hypertension, to identify new therapeutic targets.

Assistant Engineer/ Lab manager
marion.lambert@inserm.fr

After a bachelor in Industrial Microbiology, Marion first worked as a technician at the Kremlin-Bicêtre Hospital (lab of Prof. JF Delfraissy). In 2002, she joined the lab of Sophie Caillat-Zucman based over the years at Saint-Vincent-de-Paul, Necker, Robert Debré and Saint-Louis Hospitals in Paris. As long-standing cornerstone of the lab, she is now in charge of lab management duties as well as responsible for the FACS-sorting device.

Research Engineer
marie.tourret@inserm.fr

Marie obtained her PhD in immunology in 2011 from the University Paris VII. She worked on the crosstalk between CD4 T cells and dendritic cells in the lab of Claire Hivroz and Sebastian Amigorena at Institut Curie. She then joined Sophie Caillat-Zucman’s lab in 2014 to work as a Research Engineer on MAIT cells ontogeny after birth and allo-HSCT. She is now focusing on the use of MAIT cells as universal CAR T-cell therapy.

Experimental Engineer
elise.diaz@inserm.fr

Elise obtained a Master 2 in Molecular and Cellular Biology from the University Paris VII in 2015. She worked at the Institut Gustave Roussy to develop breast cancer cell models in Clara Nahmias’ lab. In 2018, she joined the lab as a research engineer to work with Jérôme Le Goff on drug discovery for the treatment of adenovirus infections following allogeneic stem cell transplantation.

• Idan MILO, Postdoc
• Aurélien GIBAUD, Technician
• Ghada BEN-YOUSEF, Experimental Engineer
• Viviane GOURNAY, Master student (M2)
• Matthieu JESTIN, Master student (M2)
• Anthony VANJAK, Master student (M2)
• Margaux GARZARO, Master student (M2)
• Maxime ENAULT, Master student (M2)
• Deborah MEYRAN, PhD student
• Robin BERNARD-BLOCH, Technician
• Armelle BOHINEUST, Postdoc
• Lucille DERIVRY, Master student (M2)
• Nicolas VALLET, PhD student
• Nana TALVARD-BALAND, PhD student
• Kristi VERA, Master student (M2)
• Grégoire MARTIN DE FREMONT, Master student (M2)
• Marwa CHBIHI, Experimental Engineer